Antibody  

CREB1 Monoclonal Antibody B-IO-10052

Overview

SynonymsActive transcription factor CREB,cAMP response element binding protein 1,cAMP response element binding protein,cAMP responsive element binding protein 1,cAMP-responsive element-binding protein 1,CREB,CREB-1,CREB1,CREB1,Cyclic AMP-responsive element-binding protein 1,MGC9284,OTTHUMP00000163864,OTTHUMP00000163865,OTTHUMP00000206660,OTTHUMP00000206662,OTTHUMP00000206667,Transactivator protein
SwissprotP16220
SourceMouse
ReactivityHuman,Mouse
ImmunogenRecombinant Protein
ApplicationWB,IHC-p
Recommended dilutionWB 1:500-1000, IHC 1:100-200
Concentration1mg/mL
ClonalityMonoclonal

Properties

Cellular localizationNucleus.
Clone No.Clone:3F1
IsotypeIgG
PurificationProtein A purification
ConjugationUnconjugated
Storage instructionsStore at -20℃. Avoid freeze / thaw cycles.
Storage bufferPBS with 0.02% sodium azide, 50% glycerol, pH7.4
BackgroundThis protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.

Images

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