Antibody  

gamma Tubulin Monoclonal Antibody B-IO-10029

Overview

SynonymsGamma-1-tubulin,Gamma-tubulin complex component 1,GCP-1,TBG1,TUBG,TUBG1,TUBGCP1,Tubulin gamma-1 chain,Tubulin,gamma 1,Tubulin,gamma polypeptide
SwissprotP23258
SourceMouse
ReactivityHuman,Mouse,Rat
ImmunogenSynthetic Peptide of Gamma Tubulin
ApplicationWB,IHC-p
Recommended dilutionWB 1:1000-2000, IHC 1:100-200
Concentration1mg/mL
ClonalityMonoclonal


Cellular localizationCytoplasm>cytoskeleton>centrosome.
Clone No.Clone:7B1
IsotypeIgG
PurificationProtein A purification
Storage instructionsStore at -20℃. Avoid freeze / thaw cycles.
Storage bufferPBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
BackgroundThis gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. TUBG1 (Tubulin Gamma 1) is a Protein Coding gene. Diseases associated with TUBG1 include Cortical Dysplasia, Complex, With Other Brain Malformations 4 and Reducing Body Myopathy. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and structural constituent of cytoskeleton. An important paralog of this gene is TUBG2.


Properties

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