Antibody  

Anti-ELK1 antibody(BL-54245)

Product information

Product name

Anti-ELK1 antibodyBL-54245

Immunogen

Synthetic peptide conjugated to KLH, surrounding amino acids 387-391 (P-R-S-P-A) of Human ELK1 (NP_001107595.1).

Host

Rabbit

Reactivity

Mouse, Rat, Human

Applications

WB, IHC-P, ICC/IF

Clonality

Polyclonal

Isotype

IgG

Purification

Immunogen affinity purified

Conjugate

N/A

Applications

WB

1/500 - 1/1000.

ICC/IF

1/100 - 1/200.

IHC-Fr

N/A

IHC-P

1/50 - 1/100. 

IP

N/A

Properties

Formulation

Liquid solution

Storage buffer

Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative, 1% BSA as stablizer and 50% Glycerol.

Storage

Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze/ thaw cycle.

Shipped at 4°C.

Shipped at 4°C.

Background
E twenty-six (ETS)-like transcription factor 1, also known as ELK1, is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. It is targeted in the nucleus by three major MAP kinase pathways as well as the CaMKII pathway. phosphorylation of nuclear Elk1 enhances its ability to bind DNA at serum response elements and stimulate transcription of immediate early genes. Elk1 plays important roles in various contexts, including long-term memory formation, drug addiction, Alzheimer’s disease, down syndrome, breast cancer, and depression. This antibody got an 62kd band in western blotting maybe duo to its phosphorylation